Gregory Blake Smith is the author of four novels. The Maze at Windermere (named one of the best books of 2018 by The Washington Post, The Seattle Times, and The Advocate), The Devil in the Dooryard, The Divine Comedy of John Venner (named a Notable Book of the Year by The New York Times), and The Madonna of Las Vegas.

His short fiction has appeared in various literary journals, including The Kenyon Review, The Antioch Review, and StoryQuarterly, and has been reprinted in such anthologies as The Pushcart Prizes and The New Generation.