Julie Neiworth receives her fifth NIH award

10 February 2021
Julie Neiworth

Julie Neiworth, Laurence McKinley Gould Professor of Natural Sciences and Psychology, was awarded an NIH AREA grant (2R15AG051940-02) entitled “Longitudinal Cognitive Behavioral Testing and Immunohistochemical Assessment of Alzheimer’s Disease Markers, Immune Response, Neurogenesis, and Cell Loss in a Natural Aging Primate Model.” This is a renewal of the former funded grant which examined how beta amyloid plaques and neural loss corresponded to failures in tasks testing working memory, rule shifting, and visual attention in cotton top tamarins as a natural process of aging. In this current renewal, Neiworth is adding a number of immune response measures, including the state of astrocytes and microglia in the brain and hyperphosphorylated tau, as well as signs of neurogenesis in aging tamarins. These are correlated with their tracked cognitive decline in life and indicate patterns related to natural aging, dementia, or Alzheimer’s disease like symptoms. This is Neiworth’s 7th federal grant obtained at Carleton, with 2 NSF grants for equipment and renovation of courses, and a total of 5 from NIH on research with undergraduate student collaborators studying cognition in birds and primates. Neiworth’s research and teaching has been funded by NIH and NSF for 24 of the 34 years she has been a faculty member at Carleton, with a total of 1.7 million dollars in funding.