Mark Mitton-Fry ’96 presents “Bugs and Drugs: Targeting MRSA with Novel Bacterial Topoisomerase Inhibitors” on Friday, February 19 at 4:30.
Methicillin-resistant Staphylococcus aureus is an antibiotic-resistant bacterial pathogen that kills more than 10,000 people per year in the United States. My research focuses on the discovery of inhibitors of two essential bacterial enzymes, DNA gyrase and topoisomerase IV. This talk will illustrate how fundamental chemical reasoning can be used to design molecules that both potently inhibit these enzymes and achieve a superior safety profile. Such compounds hold promise for the treatment of infections caused by MRSA and other drug-resistant bacteria.
Join Zoom Meeting https://carleton.zoom.us/j/97062621266
Meeting ID: 970 6262 1266 Passcode: 945583