Chemistry Department Seminar: Shana Kelley, Northwestern University
The Jerry and Jean Mohrig Lecture
"Pendulum-based sensing for continuous monitoring of biomolecules"
To put disease-related biomarkers to work for personalized monitoring of health and disease, new high-performance technologies are needed to enable rapid and sensitive analysis of proteins and other biomarkers. Electrochemical methods providing low cost and direct biomarker readout have attracted a great deal of attention for this application. Recently we developed reagentless sensors that are powerful detectors for ex vivo and in vivo protein sensing (Nature Chemistry, 2021; J. Am. Chem. Soc., 2022; Angew. Chem. 2023) as well as the analysis of viral particles in situ in the oral cavity (J. Am. Chem. Soc. 2021). This talk will summarize the development of these sensors, their application to a variety of clinical problems, and the development of a range of implatable sensors for in vivo monitoring.
*This seminar counts towards the chemistry major seminar attendance requirement for all majors not doing comps this year.